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ZYME — ZYMEWORKS INC

Reported value held$441.54M
Funds holding (latest)42
SectorHealth Care
Funds holding (Q2 2026)30
Institutional value$323.58M · 12.43M sh
New / Add / Cut / Exit2 / 11 / 16 / 5
Top-5 / Top-10 concentration71.4% / 86.2%
Institutional holdings change Reducing -14.5% (-2.11M sh)
Institutional value change Down -10.9%

As of Q2 2026, 30 SEC-registered investment managers reported holding ZYME (ZYMEWORKS INC) in their latest 13F filings, with a combined reported value of $323.58M across 12.43M shares. That is -14.5% by share count (-2.11M shares) versus the previous quarter, while reported value moved -10.9%. Ownership is concentrated: the five largest holders account for 71.4% of reported value and the top ten for 86.2%.

Compared with the prior quarter, 2 opened new positions, 11 added to existing stakes, 16 trimmed, 5 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

ZYME is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

FundQuarterSharesValuePortfolio WeightChange
BlackRock Inc history Q2 2026 4.25M $111.12M 0.00% Reduce
Vanguard Group history Q4 2025 2.33M $61.32M 0.00% Add
Morgan Stanley history Q2 2026 2.23M $58.33M 0.00% Reduce
Lone Pine Capital history Q3 2021 976.74K $28.36M 0.10% New
Citadel Advisors history Q2 2026 966.34K $25.26M 0.00% Reduce
Fidelity Management & Research (FMR) history Q2 2026 702.57K $18.37M 0.00% Add
Geode Capital Management history Q2 2026 692.41K $18.10M 0.00% Add
Goldman Sachs Group history Q2 2026 470.82K $12.31M 0.00% Reduce
Arrowstreet Capital history Q2 2026 418.50K $10.94M 0.01% Reduce
Deutsche Bank AG history Q2 2026 397.19K $10.38M 0.00% Reduce
Northern Trust Corp history Q2 2026 321.07K $8.39M 0.00% Hold
Royce & Associates history Q1 2026 299.20K $7.49M 0.07% New
Renaissance Technologies history Q4 2025 220.88K $5.82M 0.01% Reduce
Bank of America Corp history Q2 2026 219.07K $5.73M 0.00% Reduce
Wells Fargo & Co history Q2 2026 217.20K $5.68M 0.00% Add
Point72 Asset Management history Q4 2024 330.13K $4.83M 0.01% Add
Farallon Capital Management history Q1 2025 400.00K $4.76M 0.03% Reduce
Charles Schwab Investment Management history Q2 2026 152.42K $3.98M 0.00% Reduce
D. E. Shaw & Co history Q2 2026 144.81K $3.79M 0.00% Reduce
Citigroup Inc history Q2 2026 131.44K $3.44M 0.00% Add

View all 42 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ3 2021Q4 2021Q1 2022Q2 2022Q3 2022Q4 2022Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
BlackRock Inc — — — — — — — — — — — — 4.26M 4.18M 4.09M 3.79M 3.99M 4.60M 4.55M 4.25M
Morgan Stanley 2.30M 2.11M 2.33M 1.96M 5.26M 5.57M 5.56M 5.49M 4.48M 4.86M 5.11M 4.24M 5.11M 4.20M 4.07M 4.18M 3.98M 2.59M 2.48M 2.23M
Citadel Advisors 66.79K 90.12K 409.00K 270.12K 211.93K 73.67K 96.98K 101.52K 76.31K 205.27K 1.10M 621.18K 51.51K 75.26K 245.37K 310.45K 251.76K 300.25K 1.25M 966.34K
Fidelity Management & Research (FMR) 3.48M 3.49M 547.08K — — — — 24.70K 24.71K 25.59K 25.74K 1.81K 3.34K 21.97K 12.83K 3.11K 3.51K 560.09K 667.15K 702.57K
Geode Capital Management — — — — — — 31.50K 561.93K 599.46K 639.67K 668.98K 712.95K 713.91K 689.88K 705.03K 705.36K 678.64K 647.97K 659.94K 692.41K
Goldman Sachs Group 278.21K 2.52M 520.44K 1.18M — 125.06K 328.08K 190.88K 168.57K 200.62K 270.55K 173.60K 251.48K 249.96K 200.05K 428.86K 443.52K 420.21K 599.49K 470.82K
Arrowstreet Capital — — — — — — — 542.23K 472.00K 367.02K 581.56K — 407.77K — — — 313.75K 700.00K 743.90K 418.50K
Deutsche Bank AG 93.64K 125.52K 126.76K 91.66K 91.66K 715.44K 583.53K 605.13K 114.85K 888.63K 889.25K 2.36M 1.53M 1.55M 1.55M 1.54M 1.54M 1.60M 921.25K 397.19K
Northern Trust Corp 46.48K 46.43K 45.80K 12.12K 14.23K 12.83K 30.08K 421.03K 419.87K 417.15K 418.25K 364.41K 370.93K 394.83K 386.92K 349.80K 348.25K 307.98K 320.21K 321.07K
Bank of America Corp 27.61K 2.66M 4.71K 103.86K 2.79K 28.11K 108.36K 76.75K 89.70K 94.64K 53.31K 92.02K 69.73K 31.70K 62.13K 90.38K 175.33K 89.52K 236.75K 219.07K
Wells Fargo & Co 79.74K 26.47K 81.71K 100.41K 108.93K 101.33K 84.87K 206.39K 191.63K 238.25K 238.69K 170.07K 177.41K 164.06K 100.31K 166.43K 176.63K 208.31K 189.64K 217.20K
Charles Schwab Investment Management — — — — — — — 122.03K 121.87K 125.49K 125.49K 132.15K 132.80K 131.31K 133.64K 124.20K 193.36K 220.91K 185.12K 152.42K
D. E. Shaw & Co 8.25K 32.08K 437.49K 21.91K 88.48K 369.19K — 49.35K 65.07K — 27.11K 43.76K 21.78K 20.84K 63.10K 255.29K 126.92K 223.79K 235.62K 144.81K
Citigroup Inc 732 810 1.48K 613 48 25.86K 75.45K 86.02K 60.01K 25.97K 20.71K 54.71K 79.89K 83.14K 41.20K 156.00K 117.80K 111.21K 114.33K 131.44K
BNY Mellon 13.89K — — — — — — 137.10K 139.41K 276.90K 294.88K 309.70K 249.99K 120.68K 120.73K 133.09K 137.55K 128.13K 124.11K 131.11K
UBS Group AG 350 3.60K 25 25 25 25 15.07K 30.39K 37.82K 64.41K 67.42K 125.67K 135.56K 166.90K 214.30K 251.51K 51.84K 278.85K 171.78K 115.09K
Invesco Ltd 9.87K — 46.54K 54.29K 51.44K 51.18K — 36.29K 114.68K 57.09K 231.18K 67.74K 163.04K 69.38K 78.21K 89.37K 93.66K 257.58K 125.63K 112.21K
AQR Capital Management — — 12.45K — — — — 469.47K 799.68K 686.19K 489.50K 94.27K 24.86K 26.07K 48.48K 166.14K 152.63K 91.08K 90.67K 111.28K
Wellington Management Group 599.13K 2.86M 1.18M — — — — 56.38K 156.68K 205.25K 286.60K 334.78K 243.19K 219.10K 182.25K 180.69K 168.69K 181.71K 138.69K 110.01K
JPMorgan Chase & Co 30.98K 75.89K 686.78K 11 11 11 333 41.57K 36.40K 49.68K 36.58K 39.47K 39.28K 111.98K 38.41K 441.69K 33.88K 35.01K — 106.40K

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