VRTX — VERTEX PHARMACEUTICALS INCORPORATED
Index member: Invesco QQQ Trust · S&P 500
As of Q2 2026, 48 SEC-registered investment managers reported holding VRTX (VERTEX PHARMACEUTICALS INCORPORATED) in their latest 13F filings, with a combined reported value of $61.70B across 125.96M shares. That is +8.1% by share count (+9.45M shares) versus the previous quarter, while reported value moved +20.4%. Ownership is concentrated: the five largest holders account for 67.4% of reported value and the top ten for 80.2%.
Compared with the prior quarter, 1 opened new positions, 27 added to existing stakes, 18 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
VRTX is a constituent of the Invesco QQQ Trust, S&P 500 and is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
| Fund | Quarter | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|---|
| Capital World Investors history | Q2 2026 | 26.12M | $12.97B | 1.62% | Add |
| BlackRock Inc history | Q2 2026 | 24.11M | $11.98B | 0.19% | Add |
| Vanguard Group history | Q4 2025 | 24.11M | $10.93B | 0.16% | Hold |
| Capital Research Global Investors history | Q2 2026 | 19.49M | $9.68B | 1.42% | Reduce |
| Invesco Ltd history | Q2 2026 | 8.04M | $4.00B | 0.33% | Add |
| Geode Capital Management history | Q2 2026 | 6.02M | $2.98B | 0.16% | Reduce |
| Franklin Resources history | Q2 2026 | 3.35M | $1.66B | 0.38% | Add |
| Wellington Management Group history | Q2 2026 | 3.25M | $1.61B | 0.29% | Add |
| Morgan Stanley history | Q2 2026 | 3.24M | $1.61B | 0.09% | Add |
| Bank of America Corp history | Q2 2026 | 3.04M | $1.51B | 0.10% | Add |
| Norges Bank Investment Management history | Q2 2026 | 2.97M | $1.48B | 0.15% | Reduce |
| Goldman Sachs Group history | Q2 2026 | 2.53M | $1.26B | 0.11% | Add |
| Northern Trust Corp history | Q2 2026 | 2.49M | $1.24B | 0.14% | Reduce |
| Charles Schwab Investment Management history | Q2 2026 | 2.04M | $1.01B | 0.14% | Add |
| Janus Henderson Group history | Q1 2026 | 2.13M | $951.79M | 0.47% | Reduce |
| Legal & General Investment Management America history | Q2 2026 | 1.87M | $928.89M | 0.19% | Reduce |
| BNY Mellon history | Q2 2026 | 1.67M | $830.84M | 0.14% | Add |
| Deutsche Bank AG history | Q2 2026 | 1.58M | $784.39M | 0.24% | Add |
| Amundi US history | Q2 2026 | 1.55M | $768.20M | 0.19% | Add |
| Fidelity Management & Research (FMR) history | Q2 2026 | 1.46M | $723.81M | 0.04% | Reduce |
New Positions (Q2 2026)
- JPMorgan Chase & Co 45.50K sh · $22.73M
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 2.13M sh · $951.79M
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q3 2021 | Q4 2021 | Q1 2022 | Q2 2022 | Q3 2022 | Q4 2022 | Q1 2023 | Q2 2023 | Q3 2023 | Q4 2023 | Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Capital World Investors | 11.04M | 11.52M | 12.67M | 12.57M | 12.52M | 12.77M | 16.14M | 17.34M | 17.98M | 21.81M | 25.57M | 26.71M | 26.81M | 28.33M | 28.53M | 28.73M | 25.91M | 25.51M | 25.37M | 26.12M |
| BlackRock Inc | — | — | — | — | — | — | — | — | — | — | — | — | 21.79M | 21.83M | 21.78M | 21.87M | 22.25M | 23.75M | 23.97M | 24.11M |
| Capital Research Global Investors | — | — | — | — | — | — | 809.89K | 3.06M | 3.37M | 3.57M | 5.74M | 8.54M | 9.00M | 10.43M | 14.54M | 16.11M | 16.55M | 17.32M | 21.13M | 19.49M |
| Invesco Ltd | 1.21M | 1.12M | 1.21M | 1.12M | 1.32M | 1.62M | 1.86M | 1.95M | 2.02M | 2.24M | 2.09M | 1.80M | 1.94M | 1.90M | 1.85M | 1.98M | 2.10M | 2.15M | 2.56M | 8.04M |
| Geode Capital Management | 4.30M | 4.36M | 4.33M | 4.53M | 5.27M | 5.38M | 5.41M | 5.54M | 5.60M | 5.67M | 5.81M | 6.33M | 5.94M | 5.65M | 5.76M | 5.93M | 5.97M | 5.98M | 6.14M | 6.02M |
| Franklin Resources | 866.92K | 1.06M | 1.12M | 990.96K | 932.85K | 791.98K | 763.91K | 831.54K | 754.52K | 672.44K | 703.06K | 552.41K | 476.83K | 760.52K | 702.03K | 523.83K | 462.95K | 550.60K | 551.13K | 3.35M |
| Wellington Management Group | 6.09M | 6.52M | 8.05M | 8.24M | 8.03M | 6.83M | 7.52M | 7.55M | 6.53M | 5.23M | 4.56M | 4.09M | 4.80M | 5.92M | 5.45M | 4.81M | 4.77M | 3.82M | 3.21M | 3.25M |
| Morgan Stanley | 1.04M | 969.81K | 825.85K | 1.83M | 1.94M | 2.58M | 2.35M | 2.78M | 2.87M | 2.98M | 3.18M | 3.26M | 3.04M | 3.17M | 3.41M | 3.33M | 3.11M | 3.12M | 3.19M | 3.24M |
| Bank of America Corp | 3.16M | 3.10M | 3.15M | 2.71M | 2.60M | 2.59M | 2.69M | 2.48M | 2.44M | 2.66M | 2.68M | 2.61M | 2.64M | 2.44M | 2.89M | 2.83M | 2.95M | 2.94M | 2.88M | 3.04M |
| Norges Bank Investment Management | — | — | — | — | — | 2.45M | — | — | — | 3.04M | — | 3.43M | — | 3.41M | — | 3.58M | — | 3.18M | — | 2.97M |
| Goldman Sachs Group | 1.43M | 1.25M | 1.28M | 1.05M | 1.80M | 1.86M | 1.93M | 1.92M | 1.76M | 1.55M | 1.48M | 2.11M | 1.40M | 1.44M | 1.78M | 1.98M | 1.58M | 1.81M | 2.47M | 2.53M |
| Northern Trust Corp | 2.99M | 2.91M | 2.89M | 2.94M | 2.89M | 2.85M | 2.78M | 2.68M | 2.81M | 2.68M | 2.58M | 2.53M | 2.37M | 2.72M | 2.62M | 2.66M | 2.63M | 2.58M | 2.56M | 2.49M |
| Charles Schwab Investment Management | 1.24M | 1.26M | 1.33M | 1.36M | 1.39M | 1.42M | 1.44M | 1.45M | 1.47M | 1.51M | 1.56M | 1.61M | 1.63M | 1.66M | 1.73M | 1.77M | 1.83M | 1.86M | 1.92M | 2.04M |
| Legal & General Investment Management America | 2.07M | 1.90M | 2.06M | 2.20M | 2.14M | 2.03M | 2.09M | 2.13M | 2.04M | 2.43M | 2.39M | 2.42M | 2.30M | 1.88M | 1.89M | 1.89M | 1.95M | 1.97M | 1.96M | 1.87M |
| BNY Mellon | 2.09M | 2.06M | 2.00M | 2.10M | 2.08M | 2.08M | 2.04M | 2.00M | 2.01M | 1.98M | 1.87M | 1.84M | 1.79M | 1.76M | 1.71M | 1.60M | 1.57M | 1.53M | 1.59M | 1.67M |
| Deutsche Bank AG | 2.69M | 2.56M | 2.15M | 2.04M | 1.83M | 1.85M | 1.76M | 1.60M | 1.33M | 1.65M | 1.58M | 1.38M | 1.31M | 1.39M | 1.35M | 1.41M | 1.60M | 1.77M | 1.54M | 1.58M |
| Amundi US | 689.90K | 823.75K | 592.50K | 931.39K | 1.83M | 2.13M | 2.04M | 1.65M | 1.94M | 2.72M | 3.58M | 3.50M | 3.76M | 3.28M | 3.10M | 1.13M | 1.12M | 1.30M | 1.47M | 1.55M |
| Fidelity Management & Research (FMR) | 4.88M | 9.09M | 13.18M | 16.75M | 17.37M | 17.87M | 16.28M | 14.63M | 14.36M | 12.98M | 10.67M | 10.73M | 10.53M | 9.22M | 7.73M | 6.41M | 3.30M | 2.21M | 2.02M | 1.46M |
| Citadel Advisors | 1.07M | 824.79K | 779.61K | 710.90K | 557.66K | 592.01K | 363.01K | 209.91K | 305.74K | 650.08K | 377.17K | 352.19K | 353.93K | 681.08K | 386.42K | 472.73K | 584.90K | 789.96K | 631.50K | 889.63K |
| UBS Group AG | 618.11K | 445.87K | 463.39K | 308.69K | 282.78K | 608.26K | 610.45K | 582.58K | 496.06K | 575.21K | 715.78K | 724.98K | 908.22K | 1.04M | 861.42K | 776.90K | 867.45K | 651.08K | 742.72K | 803.36K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
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