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PRME — PRIME MEDICINE INC

Reported value held$205.06M
Funds holding (latest)41
SectorHealth Care
Funds holding (Q2 2026)35
Institutional value$181.89M · 49.45M sh
New / Add / Cut / Exit3 / 13 / 11 / 1
Top-5 / Top-10 concentration57.9% / 80.5%
Institutional holdings change Accumulating +18.4% (+7.69M sh)
Institutional value change Up +25.6%

As of Q2 2026, 35 SEC-registered investment managers reported holding PRME (PRIME MEDICINE INC) in their latest 13F filings, with a combined reported value of $181.89M across 49.45M shares. That is +18.4% by share count (+7.69M shares) versus the previous quarter, while reported value moved +25.6%. Ownership is concentrated: the five largest holders account for 57.9% of reported value and the top ten for 80.5%.

Compared with the prior quarter, 3 opened new positions, 13 added to existing stakes, 11 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

PRME is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

FundQuarterSharesValuePortfolio WeightChange
BlackRock Inc history Q2 2026 9.60M $35.43M 0.00% Add
ARK Invest history Q2 2026 8.35M $30.81M 0.20% Add
Vanguard Group history Q4 2025 6.47M $22.44M 0.00% Add
Balyasny Asset Management history Q2 2026 3.97M $14.65M 0.02% Reduce
Goldman Sachs Group history Q2 2026 3.43M $12.66M 0.00% Add
Casdin Capital history Q2 2026 3.17M $11.69M 0.58% Hold
UBS Group AG history Q2 2026 2.79M $10.31M 0.00% Reduce
Geode Capital Management history Q2 2026 2.71M $10.01M 0.00% Reduce
Citadel Advisors history Q2 2026 2.35M $8.68M 0.00% Add
Fidelity Management & Research (FMR) history Q2 2026 1.76M $6.50M 0.00% Hold
Two Sigma Investments history Q2 2026 1.52M $5.63M 0.00% Reduce
Farallon Capital Management history Q2 2026 1.24M $4.58M 0.02% Hold
Bank of America Corp history Q2 2026 981.34K $3.62M 0.00% Add
Charles Schwab Investment Management history Q2 2026 927.54K $3.42M 0.00% Add
Northern Trust Corp history Q2 2026 912.60K $3.37M 0.00% Add
JPMorgan Chase & Co history Q2 2026 810.10K $3.01M 0.00% New
Morgan Stanley history Q2 2026 708.96K $2.62M 0.00% Add
D. E. Shaw & Co history Q2 2026 648.94K $2.39M 0.00% Reduce
Point72 Asset Management history Q2 2026 533.55K $1.97M 0.00% New
Moore Capital Management history Q2 2026 500.00K $1.84M 0.03% Hold

View all 41 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ4 2022Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
BlackRock Inc — — — — — — — 5.27M 4.52M 4.31M 4.49M 5.65M 8.27M 8.50M 9.60M
ARK Invest 1.64M 1.92M 2.45M 2.62M 3.14M 5.99M 6.13M 5.66M 5.15M 3.10M 2.32M 5.48M 5.37M 6.25M 8.35M
Balyasny Asset Management — — — — — — 12.10K — 16.34K — — 47.87K 3.12M 4.12M 3.97M
Goldman Sachs Group — — — 58.91K 51.15K 38.18K 79.37K 220.14K 421.90K 251.40K 207.01K 410.74K 1.76M 970.42K 3.43M
Casdin Capital 734.35K 734.35K 367.18K 367.18K 367.18K 367.18K 367.18K 367.18K 367.18K 367.18K 1.57M 3.17M 3.17M 3.17M 3.17M
UBS Group AG 1.21K 4.93K 99.04K 43.77K 31.41K 42.52K 22.54K 35.02K 218.19K 117.68K 195.33K 304.77K 2.44M 2.89M 2.79M
Geode Capital Management 234.29K 240.34K 540.31K 846.64K 887.50K 916.86K 1.30M 1.36M 1.47M 1.53M 1.51M 1.77M 2.63M 2.74M 2.71M
Citadel Advisors — — — 17.72K 42.90K 171.80K 91.03K 105.59K 138.40K 88.30K 766.31K 1.23M 506.37K 598.06K 2.35M
Fidelity Management & Research (FMR) 8.46M 8.52M 4.04M 3.92M 3.93M 3.92M 3.93M 3.74M 3.80M 3.75M 3.74M 2.81M 2.18M 1.77M 1.76M
Two Sigma Investments — — — 92.99K 268.36K 508.08K 681.48K 318.57K 166.20K 258.77K 258.42K 447.67K 1.63M 1.57M 1.52M
Farallon Capital Management — — — — — 750.00K 750.00K 750.00K 750.00K 750.00K 750.00K 4.75M 1.24M 1.24M 1.24M
Bank of America Corp 47.36K 150.27K 147.51K 302.64K 470.60K 421.42K 427.40K 485.12K 430.61K 112.93K 144.51K 110.84K 648.01K 577.00K 981.34K
Charles Schwab Investment Management 71.18K 73.43K 141.14K 292.57K 296.19K 297.82K 492.26K 463.98K 484.59K 503.70K 518.63K 573.16K 936.82K 917.21K 927.54K
Northern Trust Corp 83.55K 90.08K 282.43K 332.96K 344.93K 340.00K 393.52K 524.55K 544.94K 527.31K 512.23K 607.99K 842.15K 886.72K 912.60K
JPMorgan Chase & Co 9.87K 157 30.67K 27.01K 45.52K 42.08K 38.19K 37.38K 35.64K 35.66K 33.03K 43.39K 435.71K — 810.10K
Morgan Stanley 20.39K 33.38K 57.93K 42.79K 211.73K 198.47K 183.97K 300.39K 311.28K 355.18K 587.68K 731.00K 1.17M 639.46K 708.96K
D. E. Shaw & Co — — — — — 26.67K 45.44K 139.45K — — — 2.22M 1.55M 1.39M 648.94K
Point72 Asset Management — — — — — — — — 68.53K — — — 551.03K — 533.55K
Moore Capital Management 500.00K 500.00K 446.73K 446.73K — 500.00K 500.00K 500.00K 500.00K 500.00K 500.00K 500.00K 500.00K 500.00K 500.00K
Millennium Management — 10.76K 256.56K — 134.54K 435.32K 1.33M 2.20M 1.87M 1.78M 148.00K 1.42M 51.34K — 427.10K

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