DFTX — DEFINIUM THERAPEUTICS INC
As of Q2 2026, 35 SEC-registered investment managers reported holding DFTX (DEFINIUM THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $1.92B across 45.45M shares. That is +69.9% by share count (+18.70M shares) versus the previous quarter, while reported value moved +280.6%. Ownership is concentrated: the five largest holders account for 68.5% of reported value and the top ten for 83.9%.
Compared with the prior quarter, 6 opened new positions, 22 added to existing stakes, 6 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
DFTX is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 35 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 11.23M | $528.39M | 0.01% | Add |
| Capital World Investors history | 5.37M | $252.50M | 0.03% | New |
| Fidelity Management & Research (FMR) history | 4.75M | $223.58M | 0.01% | Add |
| Geode Capital Management history | 3.64M | $171.48M | 0.01% | Add |
| Wellington Management Group history | 2.95M | $138.76M | 0.03% | Add |
| Goldman Sachs Group history | 1.80M | $84.71M | 0.03% | Add |
| Marshall Wace history | 1.30M | $61.10M | 0.05% | Add |
| Northern Trust Corp history | 1.17M | $55.00M | 0.01% | Add |
| Charles Schwab Investment Management history | 1.08M | $50.97M | 0.01% | Add |
| Two Sigma Investments history | 921.82K | $43.36M | 0.03% | Reduce |
| Balyasny Asset Management history | 897.66K | $42.23M | 0.06% | Reduce |
| BNY Mellon history | 777.27K | $36.56M | 0.01% | Add |
| Baron Funds history | 520.11K | $24.47M | 0.06% | New |
| UBS Group AG history | 499.47K | $23.49M | 0.01% | Add |
| Franklin Resources history | 486.22K | $22.87M | 0.01% | New |
| Point72 Asset Management history | 483.98K | $22.77M | 0.09% | Add |
| Morgan Stanley history | 454.91K | $21.40M | 0.00% | Add |
| Millennium Management history | 376.08K | $17.69M | 0.01% | Reduce |
| D. E. Shaw & Co history | 315.41K | $14.84M | 0.01% | Add |
| Citadel Advisors history | 284.50K | $13.38M | 0.02% | Reduce |
| JPMorgan Chase & Co history | 265.95K | $12.38M | 0.00% | New |
| Royce & Associates history | 208.55K | $9.81M | 0.08% | Reduce |
| Bank of America Corp history | 164.57K | $7.74M | 0.00% | Add |
| Manulife Financial history | 146.37K | $6.89M | 0.01% | Add |
| Deutsche Bank AG history | 142.95K | $6.72M | 0.00% | Reduce |
| AQR Capital Management history | 134.15K | $6.31M | 0.00% | Add |
| Wells Fargo & Co history | 122.03K | $5.74M | 0.00% | Add |
| Invesco Ltd history | 91.34K | $4.30M | 0.00% | Add |
| Citigroup Inc history | 79.55K | $3.74M | 0.00% | Add |
| Legal & General Investment Management America history | 74.00K | $3.48M | 0.00% | Add |
| Prudential Financial history | 15.50K | $729.12K | 0.00% | New |
| Amundi US history | 14.07K | $661.76K | 0.00% | Hold |
| Principal Global Investors history | 9.95K | $468.14K | 0.00% | New |
| PNC Financial Services history | 8.57K | $403.09K | 0.00% | Add |
| T. Rowe Price Associates history | 4.65M | $218.83K | 0.02% | Add |
Q1 2026 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 8.48M | $160.28M | 0.00% | New |
| Geode Capital Management history | 2.50M | $47.17M | 0.00% | New |
| Fidelity Management & Research (FMR) history | 1.81M | $34.20M | 0.00% | New |
| Goldman Sachs Group history | 1.68M | $31.67M | 0.00% | New |
| Citadel Advisors history | 1.49M | $28.15M | 0.01% | New |
| Wellington Management Group history | 1.30M | $24.66M | 0.01% | New |
| Balyasny Asset Management history | 1.27M | $24.08M | 0.03% | New |
| Two Sigma Investments history | 1.20M | $22.71M | 0.02% | New |
| Marshall Wace history | 1.20M | $22.70M | 0.02% | Reduce |
| Millennium Management history | 846.90K | $16.01M | 0.01% | New |
| Charles Schwab Investment Management history | 808.72K | $15.28M | 0.00% | New |
| Northern Trust Corp history | 798.99K | $15.10M | 0.00% | New |
| BNY Mellon history | 752.92K | $14.23M | 0.00% | New |
| UBS Group AG history | 493.98K | $9.34M | 0.00% | New |
| Morgan Stanley history | 438.57K | $8.29M | 0.00% | New |
| Deutsche Bank AG history | 411.83K | $7.78M | 0.00% | New |
| D. E. Shaw & Co history | 271.72K | $5.14M | 0.00% | New |
| Royce & Associates history | 234.05K | $4.42M | 0.04% | New |
| Point72 Asset Management history | 175.49K | $3.32M | 0.00% | New |
| Bank of America Corp history | 158.34K | $2.99M | 0.00% | New |
| Invesco Ltd history | 88.12K | $1.67M | 0.00% | New |
| Legal & General Investment Management America history | 59.80K | $1.13M | 0.00% | New |
| AQR Capital Management history | 57.09K | $1.08M | 0.00% | New |
| Wells Fargo & Co history | 39.97K | $755.49K | 0.00% | New |
| Janus Henderson Group history | 36.44K | $688.94K | 0.00% | New |
| Citigroup Inc history | 26.49K | $500.58K | 0.00% | New |
| Manulife Financial history | 26.40K | $499.04K | 0.00% | New |
| Amundi US history | 14.14K | $267.17K | 0.00% | New |
| PNC Financial Services history | 7.62K | $144.02K | 0.00% | New |
| T. Rowe Price Associates history | 70.00K | $1.32K | 0.00% | Add |
Q4 2025 — 2 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Marshall Wace history | 2.98M | $39.84M | 0.04% | New |
| T. Rowe Price Associates history | 52.23K | $700 | 0.00% | New |
New Positions (Q2 2026)
- Capital World Investors 5.37M sh · $252.50M
- Baron Funds 520.11K sh · $24.47M
- Franklin Resources 486.22K sh · $22.87M
- JPMorgan Chase & Co 265.95K sh · $12.38M
- Prudential Financial 15.50K sh · $729.12K
- Principal Global Investors 9.95K sh · $468.14K
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 36.44K sh · $688.94K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 |
|---|---|---|---|
| BlackRock Inc | 11.23M | 8.48M | — |
| Capital World Investors | 5.37M | — | — |
| Fidelity Management & Research (FMR) | 4.75M | 1.81M | — |
| Geode Capital Management | 3.64M | 2.50M | — |
| Wellington Management Group | 2.95M | 1.30M | — |
| Goldman Sachs Group | 1.80M | 1.68M | — |
| Marshall Wace | 1.30M | 1.20M | 2.98M |
| Northern Trust Corp | 1.17M | 798.99K | — |
| Charles Schwab Investment Management | 1.08M | 808.72K | — |
| Two Sigma Investments | 921.82K | 1.20M | — |
| Balyasny Asset Management | 897.66K | 1.27M | — |
| BNY Mellon | 777.27K | 752.92K | — |
| Baron Funds | 520.11K | — | — |
| UBS Group AG | 499.47K | 493.98K | — |
| Franklin Resources | 486.22K | — | — |
| Point72 Asset Management | 483.98K | 175.49K | — |
| Morgan Stanley | 454.91K | 438.57K | — |
| Millennium Management | 376.08K | 846.90K | — |
| D. E. Shaw & Co | 315.41K | 271.72K | — |
| Citadel Advisors | 284.50K | 1.49M | — |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details